Tuesday, October 13, 2009

It's That Time of Year Again


It's hard to believe that a year has passed since Darth Vader made a surprise appearance in our Phamacotherapy IV Class. Rumor has it that a movie is coming out capturing the drama and intensity of that moment in October of 2008.
There's no telling who might show up this year.

Monday, October 12, 2009

A Touching Article Written by a 4PD Clerkship Student



On The Shoulders of Giants
by Jena Koshaish, 4PD Student, St. Pete Campus

It’s 7:55 am and I’m checking a random vancomycin level from one of my patients drawn earlier this morning. The level is 25.5; darn, we over shot! But it’ll be ok because they have pneumonia and acute respiratory failure, we’ll need troughs around 20 to be aggressive. I’ll have to see them first and figure out what happened. I ask myself:

•Are they still on pressors (norepinephrine, vasopressin)?
•They came in septic, how is their renal function?
•What is their urine output?
•Did we draw cultures?
•Is this still empiric therapy or are we dealing with MRSA?

These are just a few of the questions I’ve been trained to ask in the intensive care unit at Lakeland Regional Medical Center.


Working the ICU is one of the most exciting places in the hospital. Usually patients are on several medications, titrated to keep the patient as hemodynamically stable and comfortable as possible while their body recovers from the trauma or illness. Pharmacists play a key role in the ICU by titrating pain and sedation medications, dosing antibiotics, optimizing blood glucose control, renally adjusting medications, monitoring therapeutic outcomes, choosing appropriate therapy for a given patient, ensuring that evidenced based medicine is practiced by referring to guidelines and primary literature to resolve questions, and as a medication expert for nurses and physicians.

During my rotation I had the privilege to work with three amazing critical care pharmacists who pushed me each and every day to expand my knowledge of the commonly used drugs in the ICU. On my first day of the rotation I assisted with CPR during a code. As I walked into the dimly lit room, the patient’s family members were standing in the corner of the room with tears welling in their eyes as their grandmother/mother was dying right in front of them. The patient was intubated and the nurse had already begun chest compressions when I entered the room. My preceptor asked if I was comfortable giving chest compressions, I nodded yes. He took my white coat and I walk toward the patient’s bed. The nurse asked me if I was ready. I thought, ready as I’ll ever be. But I just nodded yes.

She stopped compressions and I quickly aligned my hands, one on top of the other, over the patient’s chest. As I pushed down on her chest, I heard the tubing of the ventilator crackling in her bronchioles and blood was coming up from the ET tube. It was the scariest thing I’ve ever done. After about a minute and a half I asked my preceptor if I could be relieved. Shortly thereafter the physician came into the room with another family member and told us to hold CPR; the patient’s family had signed the DNR. The nurse took her hands off the patient’s chest, the ventilator and pumps were turned off, and most of the staff in the room left. I washed my hands, put my coat back on and followed my preceptor out of the room. It was perhaps the saddest, most thrilling thing I’ve ever witnessed. From then on I knew this would be a very different rotation, but most of all it would be the best rotation I’ve had so far.

Drunk or Not-Drunk? You be the Judge

At one time or another you have probably seen somebody stopped by the side of the road, performing field sobriety exercises. While many times the results are subtle and inconclusive, this case is a "no-brainer." Watch the short clip and you'll see why I call it a no-brainer.

Thanks to Dr. Derendorf for bringing this to my attention.

Friday, October 9, 2009

Crack Discovered at Crystal River Power Plant





OMG! Don't tell me that the operators of this nukie plant were found with Crack Cocaine? Oops. Should have read farther. They found a a crack in the concrete of the containment building of the Crystal River nuclear power plant, owned by Progress Energy.

Whew!!

If you want to read the whole story, here it is:
http://www.gainesville.com/article/20091009/ARTICLES/910089868








Thursday, October 8, 2009

"Just Spit." Test Detects Patients Who Don't Respond to Plavix



We have had a lot of discussion of the practical uses of pharmacogenomics. I think it is reasonable to say that the practical applications of this field of study are still emerging. The Associated Press reports that there is now a new way to determne patients' responses to Plavix.

Here's their report:


WASHINGTON -- "Just spit." With those simple instructions, health care providers in California are hoping to expand the use of genetic testing to make sure patients get the right medication.
Scripps Health hospital system has begun using a saliva-based genetic test to detect whether patients will respond to Plavix, a widely used blood thinner that usually prevents clots.
But recent studies show about one-third of people of European descent, and more than 40 percent of people of African and Asian descent don't properly respond to Plavix, putting them at increased risk of fatalblood clots. The new laboratory test from Quest Diagnostics detects four genetic mutations found in more than 90 percent of patients who won't benefit from the drug, which is marketed byBristol-Myers-Squibb andSanofi-Aventis. While older tests were capable of picking up the mutations, Quest says its test is the first designed for routine use and quick processing.
"It's so much simpler for patients because they don't have to undergo a blood draw, and that makes the process much more convenient for everyone involved," said Dr. Eric Topol, chief academic officer of Scripps Health.


Wednesday, October 7, 2009

It Took Only Two Weeks For "The Sign" to Go Up!!



Dear Pharmacy Students,
Please read below the message from the University Policy Department regarding using trees in the Health Center Courtyard to park bicycles. Please adhere to this policy and save yourself money and aggravation in reclaiming your bicycle if you choose to disobey this request. Let's not harm the trees by locking bicycles to them. There are bicycle racks around the health science center that can be utilized and which may require you to walk further into the Health Science Center than a bicycle ride to the courtyard affords.
Thank you for your cooperation with this policy.
Sincerely,
Dr. McKenzie

"An officer from UPD came in yesterday and asked that I generate an email to all of the college's students letting them know that it is not alright to lock their bikes to the trees in our courtyard. He said there's been a real issue with this lately and that it's not only unattractive, it's hurting the trees. He wanted to warn the students that if it continues, they will get ticketed or their bikes will be removed from the trees."












I told you so!!

Stuck Between "Botox" and "Toe Rings......"




On a recent trip to Los Angeles, Dr. Christian Hampp (notice: Hampp not Hemp), who recently received his Ph.D. from our College, snapped this photo of a "pharmacy" specializing in herbal medicines. Notice the juxtaposition of this shop, smack dab between a Botox Boutique and a Toe Ring Emporium. Christian makes this insightful observation: "I'm sure they do some serious medical research there..."
I wonder what the criteria are for dispensing the MJ. according to this "evaluation center." I suppose a wallet biopsy is part of the process.
Only in California.......